the effect of an aerobic exercise session in fasting versus satiety on fat and carbohydrate oxidation in hypoxia and normoxia in overweight men

Introduction: this study aimed to determine the effect of an aerobic exercise session during fasting versus satiety on fat and carbohydrate oxidation in hypoxia and normoxia in overweight men.methods: a total of 16 overweight men with a body mass index (bmi) ranging between 25-29.9 kg/m², a mean age of 30.75±6.79 years, and a maximum oxygen consumption of 24.67±4.61 liters per minute voluntarily participated in the study. each participant underwent four conditions: fasting hypoxia, normal hypoxia, fasting normoxia, and normal normoxia. during the study, the participants completed a 30-minute aerobic test on a cuclus2 bike with a heart rate (bp/m) of 60-70% in a hypoxia tent at an altitude of 3000 meters and 14.5% oxygen or in normoxia condition in the laboratory facilities of razi university of kermanshah sports sciences faculty. in the satiated state, the participants were given two pieces of toast, one tablespoon of peanut butter, and one glass of milk. the breathing gases were collected for 30 minutes to evaluate fat and carbohydrate oxidation. results: the study showed that fat oxidation was significantly higher in the fasted group compared to the satiety group (p<0.05) in both hypoxia and normoxia conditions. moreover, fat oxidation in normoxia was significantly higher than in hypoxia (p<0.05). in contrast, carbohydrate oxidation and respiratory exchange ratio were significantly lower in the fasted group compared to the satiety group (p<0.05).conclusion: based on the study’s findings, training in a hypoxia state, regardless of fasting condition, is a suitable non-invasive method to tackle obesity and overweight.