the study of changes in oxidative stress-cardiac antioxidants following the use of tribulus terrestris extract and crocin after one session of exhaustive exercise in the heart tissue of elderly male rats

Introduction:  this study aimed to evaluate the changes in cardiac oxidative stress-antioxidants following the use of tribulus terrestris extract and crocin after exhaustive exercise in the heart tissue of elderly male rats. methods: in this study, elderly male wistar rats with an average weight of 300 g and an age range of 14 to 18 months were used as the statistical population. a total of 56 rats were selected as a statistical sample and randomly divided into seven groups of 8, including control, exhausting exercise, exercise + crocin dose of 50 mg, exercise + crocin dose of 100 mg, exercise + thrush dose of 100 mg, exercise + thrush dose of 200 mg, exercise + tortoises were divided into 400 mg doses. results: the results showed that gpx concentration in training groups with doses of 50 and 100 crocin was significantly higher than in the vulnerable training group (p<0.05). in addition, gpx concentration was significantly higher in the groups with 50 and 100 doses of crocin than in the exercise groups with 100 and 200 doses of thistle (p<0.05). gpx was significantly higher in the exercise group and crocin 100 than in the exercise group and thrush 400 (p<0.01). the results also showed that sod concentration in training groups with doses of 50 and 100 crocin was significantly higher than  in the specific exercise group (p<0.01). sod concentration was significantly higher in the exercise groups with 50 and 100 doses of crocin than in the groups with 100 and 200 doses of thistle (p<0.05). also, sod was significantly higher in the exercise group and crocin 100 than in the exercise group and thrush 400 (p<0.017). conclusion: therefore, using of antioxidants is recommended to improve heart tissue function in the elderly.