lipid- lowering effects of endurance training and cinnamon extract in streptozotocin- induced diabetic rats

Introduction: diabetes is a disease caused by a lack of insulin secretion or a decrease in tissue sensitivity to insulin. the aim of this study was to investigate the lipid-lowering effects of endurance training (et) with cinnamon (c) extract in streptozotocin (stz)-induced diabetic rats. methods: thirty-two diabetic rats were divided into four groups of 8 rats, including 1) cinnamon, 2) training, 3) training+cinnamon and 4) sham groups. during four weeks, groups 1 and 3 received daily 100 mg/kg c perennially, and groups 2 and 3 ran on treadmill five times per week for 60 minutes each session at a speed of 8 to 16 m/min. data were analyzed using paired sample t test and one way anova and tukey’s post-hoc tests (p≤0.05). results: cinnamon powder, training and training+cinnamon significantly reduced tg, ldl and vldl levels as well increased hdl (p=0.001) in compare with sham group, training+cinnamon significantly reduced cho and vldl (p=0.001) in compare with sham group; training+cinnamon had more effect on decrease of cho (p=0.02) and ldl (p=0.002) as well as increase of hdl (p=0.004) rather than training. also cinnamon (p=0.03) and training (p=0.04) significantly reduced vldl in compare with sham group. conclusion(s): although training and cinnamon have lipid-lowering effect in diabetic rats, nevertheless it seems training simultaneously with cinnamon administration has better effect on improving lipid profile compare to training alone.