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   the effect of ramadan fasting on thyroid hormones in 9‐13 years old pre‐menarche girls  
   
نویسنده bahrayni shohereh ,vakili rahim ,nematy mohsen ,norouzy abdolreza ,hashemy isaac ,ebrahimi mehdi ,masoumi elham ,esmaeili habibolla
منبع journal of nutrition fasting and health - 2013 - دوره : 1 - شماره : 2 - صفحه:46 -52
چکیده    Introduction: muslims fast from dawn to dusk during ramadan. the effects of prolonged food deprivation on endocrine hormones have been studied in healthy adults but no previous study has investigated this effect on children. this study aimed to evaluate the feasible changes in serum level of thyroxin (t3), tetraiodothyronin (t4), thyroid stimulating hormone (tsh) and body composition in premenarche girls. methods: this cohort study was performed through ramadan 2012. we enrolled fiftyeight 913years old girls (weight 34.20±7.96 kg, height 142.01±7.76 cm) in two groups from (31  and 27 in fasted and nonfasted groups, respectively) prior to ramadan until afterwards. weight and height of the subjects were measured using standard methods, and then body mass index (bmi) was calculated.  body composition was measured using bio impedance analyzer (bia) method.  serum concentrations of t3, t4 and tsh hormones were measured by radio immunoassay (ria). paired ttest was used to compare result of each group before and after ramadan. independent ttest was used to compare two groups together. tanner intervention variable was controlled by generalized linear models intervening test. spss.11 software was used for data analysis. results: ramadan fasting induces a significant decrease in bmi and weight on fasted group (p=0.005, p=0.044, respectively) while a significant increase was observed in nonfasted group (p<0.001). although, t3 decreased significantly by fasting (p<0.001), it remained in the normal range. hence, t4 decreased and tsh increased slightly in both groups. conclusions: according to our findings, despite a significant reduction of t3 in fasting group, variation in thyroid hormones level remained in the normal range during ramadan fasting.
کلیدواژه islamic fasting ,puberty ,ramadan ,thyroid hormones
آدرس mashhad university of medical sciences, faculty of medicine, iran, mashhad university of medical sciences, emam reza hospital, iran, mashhad university of medical science, cancer research centers, mashhad medical school, department of nutrition, iran, mashhad university of medical science, nutrition and biochemistry research center, mashhad medical school, department of nutrition, iran, mashhad university of medical sciences, addiction research center, faculty of medicine, iran, mashhad university of medical sciences, faculty of medicine, iran, mashhad university of medical sciences, faculty of medicine, iran, mashhad university of medical sciences, school of health, department of statistic, iran
 
     
   
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