DIFFUSE LARGE B-CELL LYMPHOMA AND LUPUS VULGARIS: A TALE OF TWO DISEASES

Multi-drug resistant tuberculosis is problematic in immunocompromised individuals. in such patients, cd4 lymphocytopenia appears to correlate with the severity of the disease and with low interferon gamma production in response to infection with mycobacterium tuberculosis. treatment with interferon gamma may be a useful adjunct therapy in those patients. in this report, we describe a patient with idiopathic cd4 lymphocytopenia who presented with diffuse large b cell lymphoma after interferon gamma therapy for drug resistant tuberculosis. gamma interferon treatment may be of benefit to patients with impaired cellular immune response. before that therapy is initiated the clinicians should consider the patient's cd4 cell count considered carefully.