THE ASSOCIATION OF PERIMENOPAUSAL SYMPTOMS AND HORMONAL PROFILE

Objectıve: our aim is to determine cut-off values for perimenopausal transition period a with hormon profile which is a marker of ovarian reserve in women with 40-50 years of age. in this age group, treatment can be planned for complaints of menstruel irregularities and to prevent vasomotor symptoms. materials and methods: this is a case-control study. 194 women aged 40-50 years old submitted to our clinics were investigated between june 2008 and january 2009. we determined different cut-off values of each hormone for perimenopausal transition. conclusion: in our study, the positive probability ratios for menstruel irregularities are 1.41 with cut-off values for estradiol <55.85 pg/ml, 1.08 with cut-off values for tsh <0.98 iu/l, 1.15 with cut-off values for testosteron>23.15 ng/dl. climacteric symptoms were determined with cut-off values for fsh>6.58 iu/l, lh>3.66 iu/l, estradiol <46.7 pg/ml, testosteron>21.8 ng/dl. results: vasomotor symptoms and menstruel irregularities that change life standards can be prevented with blood hormone levels in women 40-50 years old.