unmasking coincident hodgkin lymphoma and giant cell tumor: insights from [18f] fdg pet/ct

Tenosynovial giant cell tumors represent a group of typically non-malignant tumors found within the joints and soft tissues. the occurrence of tenosynovial giant cell tumor alongside hematologic malignancies is an infrequent finding. herein, we report a patient who presented with coinciding hodgkin lymphoma (hl) and tenosynovial giant cell tumor before chemotherapy initiation. the case was discovered during initial assessment using [18f]fluorodeoxyglucose ([18f]fdg) positron emission tomography/computed tomography (pet/ct) imaging for hl staging. an unrelated hypermetabolic mass within the left knee joint led to the discovery of this unusual case, which led to a ct-guided biopsy and tenosynovial giant cell tumor discovery. this was clearly demonstrated in interim and end-of-therapy pet/ct studies when all lymphomatous lesions had resolved but the tenosynovial giant cell tumor remained. this case serves as a reminder of the intricate nature of oncological pathology and emphasizes the need for thorough and vigilant diagnostic evaluation for optimal management plan.