prevalence of hypothyroidism among patients with covid-19 in tehran city, iran

Background and purpose: numerous comorbidities are involved in the severity of the new coronavirus disease 2019 (covid-19). hypothyroidism’s impact on covid-19 is yet to be adequately understood. thyroid disorders are thought to play a role in the development and progress of covid-19. this study aimed to determine the frequency of hypothyroidism among covid-19 patients in hospitalized patients. materials and methods: this retrospective cross-sectional study was conducted at a tertiary hospital in tehran city, iran. demographic information and other specified data related to our research, mainly comorbidities, were collected using a structured questionnaire from electronic patient health records. a total of 493 medical records of covid-19 patients were used for this study according to the inclusion criteria. subsequently, the data were analyzed with spss, version 25, using descriptive and analytic statistics. results: the prevalence of hypothyroidism was 13.2% (n=65) in hospitalized covid-19 patients. this was higher (13.4% vs 2.3%) compared with the prevalence of hypothyroidism in the general iranian population. overall, in patients with hypothyroidism, about 21 patients (32.3%) expired, of whom 14 patients (66.7%) were female, and 7 (33.3%) were male. in these patients, no statistically significant difference was observed between the expired and discharged groups (adjusted odds ratio: 1.04; 95% ci 0.59-1.83; p=0.87). as a result, hypothyroidism was not linked to an increased risk of death. conclusion: hypothyroidism in hospitalized covid-19 patients appears to be low. however, it seems more prevalent in the female gender but without significant adverse effects on the risk of mortality from this disease.