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   development of porous photopolymer resin-swcnt produced by digital light processing technology using for bone femur application  
   
نویسنده akbari-aghdam hossein ,sheikhbahaei erfan ,esmaeili saeid ,motififard mehdi ,parvizi javad ,bagherifard abolfazl ,saber-samandari saeed ,khandan amirsalar
منبع the archives of bone and joint surgery - 2021 - دوره : 9 - شماره : 4 - صفحه:445 -452
چکیده    Background: although bone tissue has the unique characteristic of self-repair in fractures, bone grafting is needed in somesituations. the synthetic substances that are used in such situations should bond to the porous bones, be biocompatibleand biodegradable, and do not stimulate the immune responses. biomaterial engineering is the science of finding anddesigning novel products. in principle, the most suitable biodegradable matrix should have adequate compressive strengthof more than two megapascals. at this degradation rate, the matrix can eventually be replaced by the newly formed bone,and the osteoprogenitor cells migrate into the scaffold. this study aimed to evaluate the fabrication of a scaffold made ofpolymer-ceramic nanomaterials with controlled porosity resembling that of spongy bone tissue.methods: a compound of resin polymer, single-walled carbon nanotube (swcnt) as reinforcement, and hydroxyapatite(ha) were dissolved using an ultrasonic and magnetic stirrer. a bio-nano-composite scaffold model was designed in thesolidworks software and built using the digital light processing (dlp) method. polymer-ha scaffolds with the solvent systemwere prepared with similar porosity to that of human bones.results: ha-polymer scaffolds had a random irregular microstructure with homogenizing porous architecture. the swcntimproved the mechanical properties of the sample from 25 mpa to 36 mpa besides having a proper porosity value near55%, which can enhance the transformation and absorption of protein in human bone.conclusion: the combined bio-nanocomposite had a suitable porous structure with acceptable strength that allowed it tobe used as a bone substitute in orthopedic surgery.
کلیدواژه 3-d printing ,biocompatible materials ,carbon nanotubes ,hydroxyapatite ,tissue engineering
آدرس isfahan university of medical sciences, school of medicine, department of orthopedic surgery, iran. iran university of medical sciences, bone and joint reconstruction research center, shafa orthopedic hospital, iran, isfahan university of medical sciences, student research committee, school of medicine, iran, amirkabiruniversity of technology, new technologies research center, iran, isfahanuniversity of medical sciences, school of medicine, department of orthopedic, iran, thomas jefferson university, rothman institute, department of orthopaedic surgery, usa, iran university of medical sciences, bone and joint reconstruction research center, shafaorthopedic hospital, iran, amirkabiruniversity of technology, new technologies research center, iran, amirkabiruniversity of technology, new technologies research center, iran
پست الکترونیکی amir_salar_khandan@yahoo.com
 
     
   
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