Mid-term follow-up of the transcatheter closure of perimembranous ventricular septal defects in children using the Amplatzer

Background: the ventricular septal defect (vsd) is the most common form of congenital heart defects. the purpose of this study was to evaluate the results of the early complications and mid-term follow-up of the transcatheter closure of the vsd using the amplatzer vsd occluder. methods: between april 2012 and october 2013,110 patients underwent the percutaneous closure of the perimembranous vsd. during the procedure,the size and type of the vsd were obtained via ventriculography. a device at least 2 mm larger than the vsd diameter measured via ventriculography was deployed. the size of the vsd,size of the amplatzer,and devicesize to vsd-size ratio were calculated. after the confirmation of the suitable position of the device via echocardiography and left ventriculography,the device was released. follow-up evaluations were done at discharge as well as at 1,6,and 12 months and yearly thereafter for the vsd occlusion and complete heart block. results: the study population comprised 62 females and 48 males. the mean age and weight of the patients at procedure were 4.3 ± 5.6 years (range: 2 to 14) and 14.9 ± 10.8 kg (range: 10 to 43). the average device size was 7.0 ± 2.5 mm (range: 4 to 14). the vsd occlusion rate was 72.8% at the completion of the procedure and rose up to 99.0% during the follow-up. the most serious significant complication was complete atrioventricular block,which was seen in 2 patients. the mean follow-up duration was 10.9 ± 3.6 months. conclusion: the transcatheter closure of the perimembranous vsd was a safe and effective treatment with excellent closure rates in our study population. this procedure had neither mortality nor serious complications. © 2015,tehran heart center. all right recived.