factors associated with arrhythmia in patients with st segment elevation myocardial infarction: a single-center cross-sectional study

Background: arrhythmia is a common and clinically significant complication during hospitalization for st-segment elevation myocardial infarction (stemi). this study aimed to identify factors associated with the occurrence of arrhythmia in the acute phase of stemi.methods: this single-center cross-sectional study was conducted among adult patients hospitalized with stemi. demographic and clinical variables, including cardiovascular risk factors and disease severity (killip class, thrombolysis in myocardial infarction [timi] score, and global registry of acute coronary events [grace] score), were obtained from medical records. the primary outcome was in-hospital arrhythmia, defined as documented atrial or ventricular tachyarrhythmia or clinically significant bradyarrhythmia. factors associated with arrhythmia were assessed using bivariate analyses followed by multivariable logistic regression.results: this study involved 113 patients, with a mean age of 56.4 (11.1) years. arrhythmia occurred in 26.5% (30 patients) during hospitalization. in bivariate analyses, arrhythmia was associated with higher killip class (p<0.001), higher timi score (p=0.005), higher grace score (p=0.001), lower tricuspid annular plane systolic excursion (p=0.002), elevated serum potassium level (p=0.010), and impaired renal function, reflected by higher urea (p=0.005) and creatinine levels (p = 0.004). after multivariable adjustment, only killip class remained independently associated with arrhythmia: patients presenting with killip class i had a significantly lower risk of arrhythmia than those with higher killip classes (adjusted or, 0.404; 95% ci, 0.20 to 0.80; p=0.009).conclusion: in hospitalized patients with stemi, arrhythmic risk is chiefly driven by early clinical severity. killip class is a simple bedside predictor of in-hospital arrhythmia and can aid early risk stratification and monitoring.