Evaluation of the Correlation Between Coronary Artery Disease and Nonalcoholic Fatty Liver Disease: Is There Any Correlation?

Background: coronary artery disease (cad) and nonalcoholic fatty liver disease (nafld) are 2 common diseases around the globe. this investigation aimed to evaluate nafld prevalence in patients with cad and the potential association between nafld and cad. methods: this case-control study was performed between january 2017 and january 2018 at ziaeian hospital, tehran, iran. all patients aged between 35 and 5 years and referred for myocardial perfusion imaging were selected for the study. totally, 180 participants were divided into cad+ and cad− groups. cad was defined as stenosis of greater than 50.0% in at least 1 coronary artery. afterward, all the patients underwent abdominal sonography and laboratory tests for nafld evaluation. patients with a history of liver diseases, alcohol consumption, and drug-induced steatosis were excluded. results: the study population consisted of 122 women (67.8%) and 58 men (32.2%) at a mean age of 49.31±5.42 years. nafld was detected in 115 patients. nafld prevalence in the cad+ group was 78.9%. nafld was determined as an independent risk factor for cad (or, 3.9). conclusion: nafld prevalence was high in the cad+ group. the incidence of steatosis is on the rise in the general population. hence, considering the high prevalence of abdominal obesity, all patients with nafld should be evaluated for cad.