The Association between the PRECISE-DAPT Score and New-Onset Atrial Fibrillation in Patients with ST-Elevation Myocardial Infarction

Background: atrial fibrillation (af) is associated with increased morbidity in myocardial infarction (mi), especially thromboembolic risk increases. the precise-dapt (the predicting bleeding complications in patients undergoing stent implantation and subsequent dual anti-platelet therapy) score was created to predict the bleeding risk of dual antiplatelet therapy. the purpose of this study was to evaluate the association between new-onset af and the precise-dapt score in st segment- elevation myocardial infarction (stemi). methods: this retrospective study enrolled patients who developed stemi within 12 hours of the onset of symptoms and underwent primary percutaneous coronary intervention. the study population was divided into 2 groups of precise-dapt scores of 25 or greater and precise-dapt scores of below 25 and their baseline characteristics, as well as laboratory and echocardiography results, were compared. in-hospital new af and related events were compared between the 2 precisedapt score groups. results: from february 2015 to december 2017, this study enrolled 2234 patients with stemi at a mean age of 54.4 years. the new-onset af incidence rate was higher in the higher precise-dapt group than in the lower precise-dapt group (62 [28.7 %] vs 58 [2.9%]; p<0.001). according to the multivariate logistic regression analysis, the factors associated with new-onset af were the left atrial diameter (or=1.98, 95% confidence interval=1.34–2.93; p=0.001) and the precisedapt score (or=1.04, 95% confidence interval=1.10–1.18; p<0.001). conclusion: the precise-dapt score was associated with the development of new-onset af in our patients with stemi. further follow-up of these patients will provide clearer information.