Determining the factors associated with cardiovascular disease recurrence: Tehran lipid and glucose study

Background: several studies have emphasized the importance of cardiovascular disease (cvd) prevention. however,there is a dearth of data on the prevention of cardiovascular disease recurrence. the present study was the 1st in iran to evaluate factors associated with cvd recurrence. methods: this prospective cohort study was conducted on 483 subjects (> 30 years old) with a history of cvd who participated in the tehran lipid and glucose study and were followed up for 12 years (1999-2012). the relationships between the most important established risk factors for cvd and cvd recurrence were evaluated. results: totally,258 (53.4%) men and 225(46.5%) women at a mean age of 59.2 ± 10.7 years were recruited in the study. our results showed that over the 12-year follow-up,the incidence of a recurrent event (per 100 person-years) was 48.5. further,after controlling the possible confounding factors,the following variables had a significant relationship with cvd recurrence: age (hr = 1.02; p value = 0. 001),male sex (hr = 1.4; p value = 0.012),smoking (hr = 1.7; p value = 0.004),and increased fasting blood sugar (hr = 2.1; p value = 0.001). conclusion: we found that the established variables in the development of cvd (i.e.,age,sex,and smoking) played an important role in the risk of cvd recurrence. © 2017,tehran heart center. all rights reserved.