The Effects of A Short-Term Aerobic Training on Biochemical Cardiovascular Risk Factors and Il-6 in Obese Females

Introduction: obesity participates in the progression of systemic inflammation and cardiovascular disorders. we aimed to assess the impacts of aerobic training on serum interleukin-6 (il-6) and risk factors for cardiovascular dysfunction in obese women. methods: physically inactive, obese women matched for age (38 ± 5 years) and body mass index (bmi) (30 ≤bmi ≤36 kg/m²) were randomly divided into exercise (moderate aerobic training, 6 weeks, 3 d/wk, n = 13) and control (no training, n = 13) groups. pre- and post-training measurements of anthropometric markers, serum il-6 and cardiovascular risk factors were done. within and between groups comparisons were performed by paired sample t-test and independent sample t test, respectively. results: aerobic training induced significant decreases in body weight, bmi, body fat (%) and abdominal obesity as anthropometric markers (p < 0.05). compared to pre-training condition, serum il-6, triglyceride (tg), total cholesterol (tc) and low-density lipoprotein cholesterol (ldl-c) showed no alterations by aerobic training in the exercise group (p > 0.05). however, participants in the aerobic training group revealed a significant increase in high-density lipoprotein cholesterol (hdl-c) and a decrease in tg/hdl and ldl/hdl (p < 0.05). conclusion: short-time aerobic training does not appear to contribute to circulating serum levels of il-6 in obese females; however, it affects lipid profile and may be considered as a beneficial non-pharmaceutical intervention against cardiovascular diseases in obese women.