Evaluation of Antibacterial Activity of Iron Oxide Nanoparticles Against Escherichia Coli

Introduction: considering the usefulness of metal oxide nanoparticles in biology and biomedicine, iron oxide nanoparticles were biosynthesized using bioresource engineering to evaluate its antibacterial activity against escherichia coli. methods: macrodilution method was used for calculating the lowest concentration which prevented the growth of bacteria (minimum inhibitory concentration [mic]), and the lowest concentration that destroyed all bacterial cells (minimum bactericidal concentration [mbc]). results: the lowest concentration of iron oxide nanoparticles that inhibited the growth of e. coli (mic) was recorded at 250 μg/ml. on the other hand, the mbc of iron oxide nanoparticles was calculated at 500 μg/ml. conclusion: iron oxide nanoparticles were produced by a green and eco-friendly, simple and inexpensive method. the results showed the inhibitory effect of iron oxide nanoparticles on e. coli at 250 μg/ml. this may suggest using these nanoparticles as potential antibacterial agents.