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Acute and Recovery Changes of Tnf-Α and Il-1β in Response To Aerobic Exercise in Smokers and Nonsmokers
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نویسنده
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Seyed Hoseini Mohammad Ali ,Eizadi Mojtaba ,Amini Ashraf ,Mirakhori Zahra
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منبع
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International Journal Of Basic Science In Medicine - 2018 - دوره : 3 - شماره : 3 - صفحه:109 -113
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چکیده
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Introduction: recent evidence has shown that acute exercise affects the immune response in healthy individuals. however, the effect of aerobic exercise on inflammatory markers in smokers has not been well studied. this study evaluated acute and recovery responses of inflammatory cytokines to moderate aerobic exercise in male smokers. methods: for this purpose, 15 sedentary male smokers and 15 male non-smokers matched for age and body mass index (bmi) performed aerobic exercise involving 40-minute running at 70% of maximum heart rate (hrmax). blood samples were obtained preexercise (baseline), immediately post exercise (zero), as well as 60 minutes and 24 hours after exercise for analysis of interleukin1 beta (il-1β) and tumor necrosis factoralpha (tnf-α) levels. the data were analyzed using spss 16.0 and oneway analysis variance (anova) with repeated measures. results: no differences were observed for baseline il-1β between smokers and non-smokers. however, serum tnf-α level was significantly higher in smokers (75.1 ± 14.3) than in nonsmokers (37.2 ± 9.11) at baseline (p=0.01). aerobic exercise significantly reduced tnf-α level immediately after exercise (58.9 ± 11.6), and at 60 minutes (50.1 ± 14.8), and 24 hours (53.44 ± 12.3) post exercise in comparison with baseline (p=0.02) in smokers. tnf-α levels remained significantly higher in smokers compared to non-smokers immediately, 60 minutes, and 24 hours post exercise. il-1β levels revealed no significant differences between smokers and non-smokers at baseline, immediately, 60 minutes, and 24 hours post exercise. furthermore, exercise did not significantly affect acute or recovery changes of tnf-α and il-1β in non-smokers. conclusion: in conclusion, based on acute and recovery responses of serum tnfα to exercise, it seems that a moderate aerobic exercise may reveal beneficial effects on inflammatory profile in smokers.
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کلیدواژه
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Inflammation ,Smoking ,Aerobic Exercise ,Recovery
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آدرس
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Islamic Azad University, Parand Branch, Department Of Physical Education And Sport Sciences, ایران, Islamic Azad University, Saveh Branch, Department Of Exercise Physiology, ایران, Amirkabir University Of Technology, Department Of Physical Education And Sport Sciences, ایران, Amirkabir University Of Technology, Department Of Physical Education And Sport Sciences, ایران
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پست الکترونیکی
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mirakhori@yahoo.com
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Authors
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