investigation of serum pivka-ii levels in patients with helicobacter pylori infection and normal group

Background: helicobacter pylori is a highly prevalent microorganism and risk factor for gastric cancer. in this study, we evaluated the serum levels of pivka-ii in patients with and without h. pylori.methods: this study was performed on 90 patients (45 with h. pylori infection and 45 in the control group). after recording demographic information, serum levels of pivka-ii were measured by the elisa method.results: we found no significant difference in pivka-ii levels between all patients with and without h. pylori infection (p=0.08), but among individuals aged below 40 years old, h. pylori infection was associated with significantly lower serum pivka levels in patients vs. controls (p=0.026). among men, h. pylori infection was associated with a significantly lower serum pivka level than controls (p=0.038). among all h. pylori-infected patients, women had higher pivka levels than men (p=0.037).conclusion: our results indicate that (i) serum pivka-ii levels are lower in h. pylori-infected individuals under 40 years old and men than in non-infected controls, and ii) among all h. pylori-infected patients, serum pivka-ii levels are lower in men than women and in those under 40 years of age compared to those 40 or above.