Celiac Disease and Other Autoimmune Manifestations in a Nine-Year- Old Girl

Background: celiac disease is an autoimmune disease with a high incidence of multi-organ involvement; particularly, gastrointestinal manifestations and a doubled risk of malignancies. here, we report a case of celiac disease with autoimmune hemolytic anemia (aiha) case presentation: a nine-year-old girl presented to us with a history of abdominal pain, fever, nausea, and vomiting. her examination findings were pallor and splenomegaly; her laboratory tests showed increased liver enzymes and macrocytosis with positive coombs without a decrease in hemoglobin or high reticulocyte count. poly-autoimmunity was considered, and aiha and celiac disease were diagnosed throughout the admission following an in-depth workup. the patient responded to a strict gluten-free diet and pulse corticosteroids. this was a rare case of celiac disease presenting with such an array of signs and symptoms, with management also being distinctive and challenging. conclusion: celiac disease is very rarely associated with conditions like evans syndrome and autoimmune hemolytic anemia.still, tests of autoimmune hemolytic anemia are recommendable when a patient has celiac disease-associated anemia with a normal hematocrit level.