Eosinophilic Cholecystitis, A Rare Case Report with a Review of the Literature

Introduction: the clinical presentation of eosinophilic cholecystitis (ec) is similar to that of typical cholecystitis, commonly manifesting as right upper quadrant (ruq) tenderness along with murphy’s sign. in the literature, some reported cases have been associated with hyper-eosinophilic syndrome (hes), infections, drugs, and parasitosis; however, its etiology often remains unknown. case presentation: we report a 32-year-old woman who presented with two-day ruq pain that radiated to the right shoulder. a clinical picture of severe acute cholecystitis was recorded, and the patient underwent open cholecystectomy. microscopically, we observed an edematous wall with occasional acute and chronic inflammatory cells, predominantly composed of eosinophils. due to peripheral eosinophilia, we recommended the patient to be assessed for hyper-eosinophilic syndrome, eosinophilic gastroenteritis, and parasitosis. on follow-up, parasitic gastroenteritis was diagnosed, and the patent underwent proper treatment. conclusion: since the ec signs are similar to those of typical cholecystitis, it should not be considered a separate entity. the significance of ec diagnosis is that it can be associated with other diseases that should also be taken into consideration.