Relationship Between Colorectal Carcinoma and Adenoma Detection Rate by Colonoscopy

Introduction: in recent years, the incidence of colorectal cancer has declined dramatically. screening programs, based on endoscopic resection of polypoid precancerous lesions, have fulfilled a fundamental role in this improvement. methods: the present work took the form of a retrospective observational study of a set of patients who had undergone endoscopic resection of colonic polypoid lesions between january 2007 and december 2012. we analyzed the rate of polyps per colonoscopy, number of patients, follow-up time, and relationship with later cancer appearance. results: the study population was composed of 841 patients, including 357 women (42.4%) and 484 men (57.65%), with a sum of 7007 colorectal polyps and a mean follow-up of 66±21.84 months. during the followup period, 12 patients were diagnosed with colorectal cancer; these patients were not significantly different relative to the remaining patients in terms of rate of polyps per colonoscopy, number of advanced adenomas (z=0.11, p=0.91), and total adenomatous polyps (z=1.84, p=0.07). nevertheless, we could see that patients without colorectal cancer had a lower rate of advanced adenoma polyps per colonoscopy (z=4.61, p<0.001) and a lower raw number of polyps (z=7.09, p<0.001). conclusion: when comparing rates by number of patients, number of colonoscopic explorations, and follow-up time, the advanced adenoma rate was found to be higher in patients who later developed colorectal carcinoma. we conclude that perhaps the recommended follow-up intervals should be shortened slightly, paying special attention to follow-up in those patients who have aas in the initial colonoscopy.