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   Malignant Biliary Obstruction: Clinical Outcome of Endoscopic Intervention - An Experience of Tertiary Centers  
   
نویسنده KABIR MM ,MASUD MA ,RAHMAN MM ,HOQUE MN ,HOSSAIN SM ,BHUIYAN TM ,ALAM MM ,ARFIN MS ,RAHMAN MA ,MOHSEN AQM ,KHAN AKA
منبع journal of bangladesh college of physicians and surgeons - 2006 - دوره : 24 - شماره : 2 - صفحه:61 -68
چکیده    Most patients with malignant obstructive jaundice present at a stage when they are beyond the scope of curative surgery. endoscopic stenting is the approach of choice worldwide to improve quality of life and survival of such patients. the aim of this study was to find out overall clinical outcome of endoscopic intervention in malignant obstructive jaundice. this prospective study done in two tertiary gastroenterology centers in dhaka included consecutively admitted 79 adult patients with malignant biliary obstruction for endoscopic stenting, followed by a follow-up period of six months. outcome evaluation included success rate of stenting and drainage, complications, and mortality rate at one-month, and survival up to six-months. ercp revealed carcinoma of pancreas, periampullary carcinoma, cholangiocarcinoma, carcinoma of gallbladder, and metastasis in the biliary trees in 22 (27.8%), 22 (27.8%), 20 (25.3%), 11 (13.9%), and 04 (5.1%) cases respectively. successful stenting and drainage could be achieved in 62 (78.5%) and 58 (73.4%) cases. stent blockage (23.9%) and cholangitis (19.4%) were the main complications. total death at one-month was nine of 55 (16.4%), and 21 (38.2%) patients survived up to six-months, with no difference in one-month mortality rate among the malignancies (p>0.05). stenting prolonged six-month (88.2%) and mean survival (121.2±67.7 days) only in patients with periampullary carcinoma (p<0.001). endoscopic stenting can safely be done in malignant biliary obstruction to offer palliation with an outcome, which is not unsatisfactory.
آدرس Bangladesh Institute of Research & Rehabilitation in Diabetes, Endocrine & Metabolic Disorders (BIRDEM) Hospital, Department of Gastrointestinal, Hepatobiliary & Pancreatic Disorders (GHPD), Bangladesh, Dhaka Medical College, Bangladesh, Sahabuddin Medical College, Bangladesh, BIRDEM Hospital, Department of Gastrointestinal, Hepatobiliary & Pancreatic Disorders (GHPD), Bangladesh, Gastroliver Hospital & Research Institute, Bangladesh, BIRDEM Hospital, Department of Gastro-intestinal, Hepatobiliary & Pancreatic Disorders (GHPD), Bangladesh, BIRDEM Hospital, Department of Gastrointestinal, Hepatobiliary & Pancreatic Disorders (GHPD), Bangladesh, BIRDEM Hospital, Department of Gastrointestinal, Hepatobiliary & Pancreatic Disorders (GHPD), Bangladesh, BIRDEM Hospital, Department of Gastrointestinal, Hepatobiliary & Pancreatic Disorders (GHPD), Bangladesh, BIRDEM Hospital, Department of Gastrointestinal, Hepatobiliary & Pancreatic Disorders (GHPD), Bangladesh, BIRDEM Hospital, Department of Gastrointestinal, Hepatobiliary & Pancreatic Disorders (GHPD), Bangladesh
 
     
   
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