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Oral Azithromycin Pulse Therapy and Daily Topical Benzoyl Peroxide in the Treatment of Acne Vulgaris: An Open Clinical Trial Study
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نویسنده
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akter b
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منبع
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journal of bangladesh college of physicians and surgeons - 2018 - دوره : 36 - شماره : 1 - صفحه:11 -15
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چکیده
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Introduction: combination therapy is an effective approach to simultaneously target multiple pathogenic factor of acne. a unique combination of oral azithromycin pulse therapy and daily topical benzoyl peroxide has been developed for treatment of acne. material & methods: it was an open, controlled, clinical trial, conducted on 37 out patients with acne vulgaris. patients were clinically assessed at baseline &at week 0, 4, 8 and 12. evaluation included success rate (subjects clear or excellent improvement, good response), lesion count & percentage change in lesion count from baseline, cutaneous tolerability & adverse events. results: the combination of oral azithromycin pulse therapy & daily topical benzoyl peroxide was very safe & effective with significant differences in percentage of lesion count change observed as early as 1-4 weeks .adverse events were more frequent with the combination therapy that occurred early in the study &were transient. conclusion: this study revealed that combination regimen of azithromycin &benzoyl peroxide (4%) is indeed very much efficacious & safe in the management of acne vulgaris.
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کلیدواژه
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To evaluate the efficacy ,safety of oral azithromycin pulse therapy ,daily topical benzoyl peroxide (4 ,) combination in the treatment of acne vulgaris
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آدرس
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combined military hospital (cmh), bangladesh
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پست الکترونیکی
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niraa3620@gmail.com
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Authors
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