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   Oral Azithromycin Pulse Therapy and Daily Topical Benzoyl Peroxide in the Treatment of Acne Vulgaris: An Open Clinical Trial Study  
   
نویسنده akter b
منبع journal of bangladesh college of physicians and surgeons - 2018 - دوره : 36 - شماره : 1 - صفحه:11 -15
چکیده    Introduction: combination therapy is an effective approach to simultaneously target multiple pathogenic factor of acne. a unique combination of oral azithromycin pulse therapy and daily topical benzoyl peroxide has been developed for treatment of acne. material & methods: it was an open, controlled, clinical trial, conducted on 37 out patients with acne vulgaris. patients were clinically assessed at baseline &at week 0, 4, 8 and 12. evaluation included success rate (subjects clear or excellent improvement, good response), lesion count & percentage change in lesion count from baseline, cutaneous tolerability & adverse events. results: the combination of oral azithromycin pulse therapy & daily topical benzoyl peroxide was very safe & effective with significant differences in percentage of lesion count change observed as early as 1-4 weeks .adverse events were more frequent with the combination therapy that occurred early in the study &were transient. conclusion: this study revealed that combination regimen of azithromycin &benzoyl peroxide (4%) is indeed very much efficacious & safe in the management of acne vulgaris.
کلیدواژه To evaluate the efficacy ,safety of oral azithromycin pulse therapy ,daily topical benzoyl peroxide (4 ,) combination in the treatment of acne vulgaris
آدرس combined military hospital (cmh), bangladesh
پست الکترونیکی niraa3620@gmail.com
 
     
   
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