relationship between myocardial right ventricular relaxation time and pulmonary artery pressure in patients with pulmonary arterial hypertension

Introduction: recent developments in echocardiography made assessing pulmonary arterial hypertension (pah) in the heart, a suitable choice. this study aimed to investigate the association of myocardial right ventricular relaxation time and systolic pulmonary artery pressure (spap) in pah patients.materials and methods: the present study evaluated 74 patients with pah (n=49) and age- and sex-matched healthy controls (n=25). all patients underwent transthoracic echocardiography. we evaluated the right ventricular (rv) function's echocardiographic parameters, including ivrt, ivct, s, e, a, s’, e’, a’, et, dt, tapse, fac, and spap.results: we found no significant differences in age and gender between the two studied groups (p>0.05). however, we observed a significant difference in ivrt, ivct, e’, a’ (p=0.004), a, s’, dt, tapse, fac and spsp (p<0.001 for all cases) between two studied groups. unlike the control group, we revealed a significant correlation between s’ and e’ (r=0.45, p=<0.001), s’ and a’ (r=0.66, p=<0.001), s’ and fac (r=0.3, p=0.035), a and a’(r=0.4, p=0.004), tapse and fac (r=0.82, p=<0.001), tapse and spap (r= -0.43, p=0.002), mpi and a (r= -0.35, p=0.013), mpi and et (r= -0.72, p=<0.001), e/a and e/e’(r=0.47, p=<0.001), and bsa and s’ (r= -0.3, p=0.011). in addition, no meaningful association was found between spap and ivrt and ivct (p>0.05).conclusion: our findings revealed that ivrt and ivct might not be affected by the spap and, therefore, could be used in the assessment of right ventricular function in patients with pah.