prognostic impact of thrombolysis in myocardial infarction risk index on hospitalization mortality of patient with acute pulmonary embolism

Introduction: acute pulmonary embolism (pe) is one of the deadly cardiovascular diseases.one of the indexes proposed in these patients for risk stratification is the thrombolysis inmyocardial infarction (timi) risk index (tri), which includes three parameters of systolic bloodpressure, age, and heart rate. this study aimed to evaluate the predictive value of tri on inhospitaland 30-day mortality of pe patients.materials and methods: this cross-sectional study included 345 patients who werediagnosed with acute pe in madani heart center from january 2012 to january 2017.demographic characteristics, hemodynamic findings upon first admission, type of treatment (i.e.,thrombolytic, anticoagulant, or surgery), as well as in-hospital and 30-day outcomes wererecorded for all patients. the tri and simplified pulmonary embolism severity index (pesi)were calculated for all patients.results: the overall and in-hospital mortality rates were 8.7% and 8.1%, respectively. themortality group were significantly older and had significantly higher heart rates, cardiactroponin levels, simplified pesi scores, and tri followed by lower systolic blood pressure ando2 saturation. moreover, the tri obtained specificity, sensitivity, positive, and negativepredictive values of 98.78%, 25.25%, 89.29%, and 76.66%, respectively, using receiveroperating characteristic curves and a cut-off value of 36.73. using the multiple logisticregression analysis we found that tri>36.73, older age, higher heart rate and lower sbp couldpredict 30-day mortality.conclusion: the results showed that the risk of in-hospital mortality is higher with anincrease in tri. furthermore, despite the high specificity, lower sensitivity limits its utility.