Mortality Predictors in Covid-19 Positive Patients with Fractures: A Systematic Review

Objective: to analyze the factors associated with mortality in fracture patients with concomitant covid-19 infection based on the available published data. methods: keywords such as “fracture” and “covid or covid-19” were searched through three major databases includes pubmed, embase, and google scholar. selection criteria were all published reports providing the mortality related information of covid-19 positive fracture patients. published papers containing mortality data of covid-19 positive fracture patients were considered for qualitative review. for meta-analysis, the presenting individual’s data were considered to study the different parameters association with mortality. results: the rate of mean mortality in covid-19 positive fracture patients was 34%, and 91.7% of patients had hip fractures. older age and hip fractures had a significant association with higher mortality rates in covid-19 positive fracture patients. conclusion: the mortality rates are considerably higher in covid-19 positive patients with fractures compared to covid-19 positive patients without fractures and to the covid-19 negative fracture patients. early surgical intervention should be preferred in hip fractures among covid-19 positive patients for general stabilization and improved respiratory function. older age and hip fractures are the main predictors of mortality in these patients.