Antimicrobial Survey of Local Herbal Drugs against Acinetobacter baumannii Isolated from Patients Admitted to a Level-I Trauma Center

Objective: to determine the antimicrobial activity and entity of several local herbal plants against acintobacters isolated from trauma patients admitted to a level-i trauma center. methods: the antibacterial activities of the satureja bachtiarica oil and some selected iranian medicinal plants (artemisia sieberi and tanacetum dumosum belonging to the asteraceae/compositae; salvia mirzayanii and mentha mozaffarianii belonging to the lamiaceae/labiatae) were assayed on a. baumannii by microdilution and agar disc diffusion methods. having obtained the acceptable antibacterial data, the shade- dried aerial parts of the plants were extracted by hydrodistillation method using clevenger apparatus according to european pharmacopeia for 3 h. the analysis of s. bachtiarica essential oil accompanied by other herbal drug oils were performed by using gc/fid and gc/ms methods. results: outcomes revealed that the s. bachtiarica essential oil exhibited the potent antibacterial capability against acinetobacter strains in comparison with colistin, as a positive control. for s. bachtiarica, the growth inhibition zone and minimum inhibitory concentration (mic) values were 21 mm and 0.5 mg/ml, while, for colistin, the data were in order: 8 mm and 0.016 mg/ml. consequently, gc/ms outcomes demonstrated that the major components of the essence were carvacrol (48.6%), followed by p-cymene (16.6%), γ- terpinene (6.9%) and linalool (5.3%). conclusion: based on the considerable inhibitory activity against nosocomial infections by essential oil of s. bachtiarica, it could be considered as the suitable candidate in the food industry and pharmaceutical uses.