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Anti-Oxidant Protective Effects of Cassia Alata in Rats Exposed to Carbon Tetrachloride
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نویسنده
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WEGWU M.O. ,AYALOGU E.O. ,SULE O.J.
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منبع
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journal of applied sciences and environmental management - 2005 - دوره : 9 - شماره : 3
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چکیده
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The protective activity of cassia alata against carbon tetrachloride (ccl4) – induced hepatotoxicity in rats was assessed. crude extracts of petals of the plant in 0.5% ethanol were administered by intubation for 14 days prior to injection of 0.5ml kg-1 ccl4 into the rats. serum aspartate aminotransferase and alanine aminotransferase levels, 18 hours after ccl4 administration, decreased significantly (p < 0.05) in rats treated with the extracts than in ccl4 – treated rats only. these findings suggest that cassia alata may be protective against hepatotoxin-induced liver damage in rats.
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آدرس
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University of Port Harcourt, Department of Biochemistry, Nigeria, University of Port Harcourt, Department of Biochemistry, Nigeria, Niger Delta University, Departments of Medical Biochemistry, Nigeria
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Authors
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