Characterization and Evaluation of Antibiotic Susceptibility Pattern of Coagulase Negative Staphylococci Isolated from Common Clinical Specimens in a Central Hospital in Delta State, Nigeria

The emergence of coagulase negative stapylococci as major pathogens reflects the increased use of implants in hospitals. fifty-four coagulase-negative staphylococci were isolated from a total of 242 clinical specimens at the central hospital, kwale. all isolates were identified by standard bacteriological methods. antibiotic sensitivity test was performed on all coagulase- negative staphylococci (cons) isolates using the modified kirby-bauer method with 10 different antibiotics. staphylococcus epidermidis was the commonest species (83.3%), while staphylococcus saprophyticus was 16.7%, mainly from urine samples. highest sensitivity was found with ofloxacin (81.5%), followed by ciprofloxacin (77.8%) and, highest resistance occurred with cotrimoxazole to which no isolate was sensitive.