Pediatric dental management of patients with von Willebrand disease: reporting the cases of two brothers

Von willebrand disease -vwd- is a genetic hematologic condition characterized by an impaired function of the von willebrand factor of coagulation. it is the most common hereditary blood-clotting disorder in humans. dental management of this type of disease includes thorough cooperation with the patient’s hematologist and rigorous medical and dental treatment protocols. the former aspect includes pre-operative, intra-operative, and post-operative hemostasis controls, often with factor replacement, and the latter may dictate radical decisions in the interest of patient’s general health status. this clinical paper addresses the dental management of two brothers affected with von willebrand disease and discusses the rationale for treatment choices.