The efficacy of OsteoBiol Gen-Os® on postextraction alveolar ridge preservation: a blind clinical radiological trial in humans

An important issue facing most dental clinicians is whether the bone replacement grafts help in preserving alveolar bone in post-extraction period, and whether they will limit or reduce alveolar bone height's shrinkage, when compared to sites not receiving a graft material. the aim of this study was to compare post-extraction vertical bone loss between two groups using cone beam computerized tomography (cbct), where one group received osteobiol gen-os® (xenograft) and collaplug® (collagen sponge) and the other group only received collaplug®. material and methods: fourteen patients requiring tooth extraction were enrolled in the study. they were divided in two groups: group i (study -or test- group of seven patients who received osteobiol gen-os® and collaplug®), and group ii (control group of seven patients who only received collaplug® in extraction sites). vertical alveolar ridge changes were studied on cbct images, in the two groups, from time of extraction to four months following extraction. results: vertical bone loss was significantly less in test group (0.66 ±0.071 mm) compared to control group (0.967 ±0.13 mm). conclusion: in alveolar ridge preservation, the use of xenograft in conjunction with a collagen sponge is more efficient than the sole use of a collagen sponge, in a fresh extraction socket.