Chronic Inflammatory Demyelinating Polyneuropathy in Children: A Review Of Clinical Characteristics and Recommendations For Treatment

context: chronic inflammatory demyelinating polyradiculopathy (cidp) is an acquired and autoimmune neuropathy, characterized by a chronic, rapidly progressive, symmetric weakness. in children, abnormal gait is as a first symptom of muscle weakness.evidence acquisition: the diagnosis of cidp is on the basis of clinical characteristics, electrodiagnostic that shows the severity of the disease, lumbar puncture and spine magnetic resonance imaging (mri).results: the first-line treatments in childhood cidp are intravenous immunoglobulin (ivig), corticosteroids, and plasmapheresis. response to first-line therapies is usually satisfactory; nevertheless, recommendations regarding the choice of second-line therapy can only be prepared on the basis of the existing practice described in some of the case reports.conclusions: this review demonstrated the clinical presentation, diagnosis, and treatment of childhood cidp.