acute generalized exanthematous pustulosis due to cephalexin: a case report and literature review

Introduction: acute generalized exanthematous pustulosis (agep) is a cutaneous reaction thatmay appear after using certain medications, such as cephalexin. this disease is characterized bynon-follicular sterile pustules, erythematous, urticaria, fever over , and leukocytosis. cephalexinbelongs to the family of β-lactam antibiotics, which are widely used to treat infections. however,cephalexin skin sensitivities have been reported rarely. herein, in this case, we aimed to report apatient presented with agep due to cephalexin usage.case presentation: a 12-year-old boy presented with warm skin lesions that gradually appearedon the limbs, trunk, face, and neck after using cephalexin powder on his left leg injury. becauseof his symptoms, acetaminophen, fexofenadine hydrochloride, loxoprofen sodium, and ointment,including difluprednate and hydrocortisone, were prescribed. over time, the patient’s feversubsided, and 8 days later, the symptoms of agep, including urticaria, erythematous, and pustulesin the neck and trunk, disappeared.conclusions: cephalexin is one of the antibiotics that doctors and patients consider when thereis a possibility of infection. agep is a rare but severe reaction that can manifest as skin rashesin any age and sex following the use of cephalexin, so the patient should be careful when usingthis antibiotic.