the ophthalmological manifestations of various inborn errors of metabolism: a narrative review

Context: inborn errors of metabolism or inherited metabolic disorders (imd) are a class of genetic disorders that occur because of single-gene defects. evidence acquisition: in this narrative review article, the authors searched institute for scientific information (isi), web of science, pubmed, and google scholar for the relevant evidence. results: the ocular manifestations of imds can be distinguished in different diseases such as albinism, cystinosis, homocystinuria, and sulfite oxidize deficiency, mannosidosis, fucosidosis, sialidosis, etc. conclusions: due to the direct toxic mechanisms of abnormal metabolites on eyes and regarding the effect of eye monitoring on the follow-up, management, and treatment, a detailed ophthalmological assessment is essential.