the effect of cordia myxa mouthwash on the incidence and severity of stomatitis in leukemia patients undergoing chemotherapy: a protocol study

Background: stomatitis, or oral inflammation, is one of the common complications in patients undergoing chemotherapy, causing pain, discomfort, infection, and prolonged hospitalization.objectives: the purpose of this study is to investigate the effect of cordia myxamouthwash on preventing stomatitis in patients undergoing chemotherapy. methods and result: this study will be a double-blind, single-center, randomized controlled clinical trial focusing on 60 patients undergoing chemotherapy. the samples will be randomly divided into intervention and control groups. in addition to receiving the routine betadine mouthwash, participants in the intervention group will receive a solution of 30 drops of 5% c. myxaformulation in 20 cc of water, and they will be asked to put the solution in their mouth, swirl it for a minute, and then spit it out. in the control group, in addition to betadine mouthwash, a sterile water placebo (with the same taste and smell) will be used. the data will be analyzed based on statistical tests using spss version 22. conclusions: if this intervention proves effective in improving access and adherence to treatment, it would represent a step forward in addressing a chronic health problem common among leukemia patients undergoing chemotherapy. given its natural essence and the fact that it is not associated with any complications, c. myxa mouthwash can be used safely alongside the main treatment to prevent and reduce the severity of mouth ulcers caused by chemotherapy.