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New era for management of chronic hepatitis C virus using direct antiviral agents: A review
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نویسنده
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elbaz t. ,el-kassas m. ,esmat g.
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منبع
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journal of advanced research - 2015 - دوره : 6 - شماره : 3 - صفحه:301 -310
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چکیده
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The pegylated interferon regimen has long been the lone effective management of chronic hepatitis c with modest response. the first appearance of protease inhibitors included boceprevir and telaprevir. however,their efficacy was limited to genotype 1. recently,direct antiviral agents opened the gate for a real effective management of hcv,certainly after fda approval of some compounds that further paved the way for the appearance of enormous potent direct antiviral agents that may achieve successful eradication of hcv. © 2014.
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کلیدواژه
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Direct antiviral agents (DAA); HCV; Polymerase inhibitors; Protease inhibitors
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آدرس
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endemic medicine and hepatogastroenterology department,faculty of medicine, Egypt, hepatology department,national hepatology and tropical medicine research institute, Egypt, endemic medicine and hepatogastroenterology department,faculty of medicine, Egypt
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Authors
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