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   Chemical Composition, Antimicrobial and Antioxidant Activities of Crupina crupinastrum as a Medicinal Plant Growing Wild in West of Iran  
   
نویسنده fathollahi rohollah ,dastan dara ,lari jalil ,masoudi shiva
منبع journal of reports in pharmaceutical sciences - 2018 - دوره : 7 - شماره : 2 - صفحه:174 -182
چکیده    In this study, the hydro-distilled volatile oil from the aerial parts of crupina crupinastrum was investigated by gc-ms and gc-fid. a total of 25 compounds representing 86.4% of the volatile oil were identified. the main constituents were linoleic acid (19.1%), n-decane (12.4%) and ethyl hexadecanote (7.8%). the antioxidant activity of essential oil and methanolic extract was evaluated with dpph radical scavenging activity. the total phenolic and flavonoids contents were also determined spectrophotometerically. the antimicrobial activity of essential oil of c. crupinastrum was examined against four gramnegative and five gram-positive bacteria. the preliminary phytochemical analysis of the methanolic extract carried out using standard procedures. the data of this study suggests that c. crupinastrum has potential for application as an antioxidant and antimicrobial agent in pharmaceutical and food industries.
کلیدواژه Antibacterial ,Antioxidant ,Crupina crupinastrum ,Essential Oil ,Phytochemical Screening
آدرس payame noor university, department of chemistry, Iran, hamadan university of medical sciences, medicinal plants and natural products research center, school of pharmacy, department of pharmacognosy and pharmaceutical biotechnology, Iran, payame noor university, department of chemistry, Iran, islamic azad university, central tehran branch, department of chemistry, Iran
 
     
   
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