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   hypoglycaemia and antioxidants potential of sorghum bicolor seeds  
   
نویسنده omiyale olumakinde charles ,atanda dorcas ,obasi daniel ebubechi ,isshak fawaz ,kokelu anthony nduka ,didigwu obinna kenneth ,adeyemi surajudeen adewumi ,amamba blessing chinyere ,toyobo taiwo ,oni-adimabua oluwaseun nneka ,edema victoria biola ,fagbenro pelumi habeeb
منبع international journal of advanced biological and biomedical research - 2024 - دوره : 12 - شماره : 4 - صفحه:331 -341
چکیده    One of the most significant seeds crops in the world, sorghum bicolor, is recognized for its vibrant phytochemicals, which may have medicinal uses. the aim of this study is to determine the antioxidant and hypoglycemic properties of sorghum bicolor seeds. the ethanol and methanol extracts of these plants were subjected to antidiabetic conditioning using methods such as glucose adsorption capacity, muscle glucose uptake, and yeast glucose uptake, while iron-sulphate and sodium nitroprusside-induced lipid peroxidation were used to analyse the antioxidant capabilities. the results demonstrate that sorghum bicolor’s ethanol and methanol extracts adsorbed glucose, with the concentration of glucose adsorption rising as extract concentrations did. the muscle glucose uptake levels and glucose adsorption capabilities differed significantly (p ≤0.05). the yeast cells’ ability to absorb glucose was likewise enhanced by the plant extracts, and glucose uptake was measured. in the brain and liver of iron-sulfurate-induced lipid peroxidation, the mda (malondialdehyde) product was considerably (p ≤0.05) elevated. however, there was no significant change in the mda product of sodium nitroprusside-induced lipid peroxidation. the ethanol and methanol extracts of sorghum bicolor were found to have further potential as antioxidant and anti-glycemic agents, respectively, in this study.
کلیدواژه sorghum bicolor ,antioxidant ,hypoglycemic ,lipid peroxidation
آدرس university of lagos, college of medicine, department of pharmacology, nigeria, lagos state university, faculty of life sciences, department of biochemistry, nigeria, university of ibadan, faculty of clinical sciences, department of medicine and surgery, nigeria, kwame nkrumah university of science and technology, department of food science and technology, ghana, university of calabar, department of human physiology, nigeria, university of nigeria nsukka, faculty of pharmaceutical sciences, department of pharmaceutical and medicinal chemistry, nigeria, osun state university osogbo, faculty of basic and applied sciences, department of chemical science, nigeria, university of ibadan, faculty of basic medical science, department of biochemistry, nigeria, university of ibadan, department of biochemistry, nutritional and industrial biochemistry unit, nigeria, red river polytech college, faculty of clinical sciences, department of science laboratory technology, nigeria, olabisi onabanjo university, faculty of science, department of physiology, nigeria, lagos state university, faculty of science, department of biochemistry, nigeria
پست الکترونیکی fhabeebpelumi@gmail.com
 
     
   
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