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antifungal potential of honey against dermatophytes: a comprehensive study on isolates from children and farmers in wukari, north east nigeria
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نویسنده
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ifeoma anyiam vivan ,kenneth imarenezor edobor peter ,abel abhadionmhen onolunosen ,ngozi ofiri pascal
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منبع
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international journal of advanced biological and biomedical research - 2024 - دوره : 12 - شماره : 2 - صفحه:206 -217
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چکیده
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This study explores the antifungal properties of honey against dermatophytes isolated from children and farmers in wukari, nigeria, addressing the global public health concern of dermatophytosis. dermatophytes such as trichophyton species, epidermophyton floccosum, and microsporum canis were identified in skin, hair, and nail samples. through agar well diffusion and minimum inhibitory concentration (mic) methods, the study demonstrated concentration-dependent inhibitory effects of honey on these dermatophytes, with substantial zones of inhibition. notably, trichophyton species exhibiting a maximum zone diameter of 36 mm at 100% honey concentration followed by epidermophyton floccosum (25 mm) and microsporum canis (40 mm). mic results at a 60% honey dilution showed very scanty growth for trichophyton species and epidermophyton floccosum, while microsporium canis displayed no growth after both five and seven days of culture. the findings suggest honey’s potential as an alternative antifungal agent against dermatophytes amid increasing antimicrobial resistance. future research should focus on identifying honey’s specific bioactive components and conducting clinical trials for practical application.
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کلیدواژه
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dermatophytosis ,honey ,antifungal activity ,antimicrobial resistance
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آدرس
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federal university otuoke, faculty of science, department of microbiology, nigeria, federal university otuoke, faculty of science, department of microbiology, nigeria, federal university wukari taraba state, department of microbiology, nigeria, prevention of mother to child transmission (pmtct), excellence community education welfare scheme (ecews), nigeria
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پست الکترونیکی
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pascalofiri@yahoo.com
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Authors
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