mapping of transcription factor binding region of kappa casein (csn3) gene in iranian bacterianus and dromedaries camels

Κ-casein is a glycosilated protein in mammalian milk that plays an essential role in the milk micelles. control of κ-casein expression reflects this essential role, although an understanding of the mechanisms involved lags behind that of the other milk protein genes. transcriptional regulation, a first mechanism for controlling the development of organisms, is carried out by transcription factors binding sites (tfbss). we determined the 5’ region for iranian dromedaries and bactrianus camel κ-casein gene. we also determine their regulatory tfbss regions. this region contained 14 potential tfbss the four of them c/ebp-α, oct1, mgf/stat5 and tpb have almost perfectly conserved.