microscopic study of histological changes the use of ileal mucosa as a bladder (radical cystectomy - case report)

Cancer can significantly have ruining effects on very high of human beings, social, and economic condition. bladder cancer has been reported as one of the most common cancers and the incidence rates of this cancer is increasing across the world. cystectomy is a surgery to remove the urinary bladder. in the present study a part of the ileum is used instead of bladder. this study deals with mucosa morphological changes induced in a patient with history of cystectomy surgery, an 8-year follow-up. the specimens were stained with hematoxylin-eosin in order to examine the changes in the thickness of the mucosa processed for light and electronic microscopy. during examining microscopic slides simple epithelial tissue with goblet cells were observed. also, lieberkuhn gland and loose connective tissue were seen. the existence of thick layers at cylindrical cells, it could be due to urinating. finally, goblet cells maybe loss the property of mucosa secretion.