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Synthesis and Biological Activity of a New Schiff Base Ligand Pyridazine Based
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نویسنده
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fekri m. h. ,darvishpour m. ,khanmohammadi h. ,rashidipour m.
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منبع
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journal of chemical health risks - 2013 - دوره : 3 - شماره : 4 - صفحه:63 -68
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چکیده
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In this work 3, 6-bis (2-[2-sulfanyl-ethylimino)-methyl]-4-(4-nitro-phenylazo)-3-metoxy-phenol) pyridazine (2) was prepared and its antibacterial properties have studied. the structures of all the newly synthesized compounds have been comfirmed by elemental analysis, ir, 1h-nmr. anti bacterial effects of compounds (1 and 2) have been studied. following concentrations of materials were used: a=0.005 g/ml and b=0.01 m. study was done on two strains of s.aureus and e.coli that experiments were done in trypticase soy broth (tsb) and nutrien agar (tsb; difco laboratory). it is likely that these synthetic materials exert higher antibacterial effect on gram positive bacteria in comparison with gram negative.
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کلیدواژه
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Schiff base ,Di-azo compound ,Pyridazine ,Antibiotic ,O-vanilin
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آدرس
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ayatollah alozma boroujerdi university, department of chemistry, ایران, ayatollah alozma boroujerdi university, department of chemistry, ایران, arak university, department of chemistry, ایران, islamic azad university, khorramabad branch, young researchers club, ایران
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Authors
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