comparison of six weeks of weight training with a combination of beta‑hydroxy‑beta‑methylbutyrate and creatinine and two weeks of non-training on the concentrations of some blood biochemical factors in male powerlifting athletes

In this study, concentrations of some blood biochemical factors in male powerlifting athletes were compared through 6 weeks of weight training with combined beta-hydroxy-beta-methylbutyrate (hmb) and creatinine (cr) supplements and 2 weeks of non-training. thirty-two male athletes aged 21-30 years were randomly divided into four groups of eight individuals: cr, hmb, hmb + cr, and weight training. the training program was designed for 6 weeks and four sessions per week. the hmb group consumed 3 g of the supplement on training days and 1g on  non-training days, the cr group  consumed  three servings of  5 g on  training days and 5 g  on non-training days, and the hmb +cr group consumed the same amount of hmb and cr supplements as the hmb and cr groups.  during 2 weeks of non-training, the hmb, cr, and hmb + cr groups received daily 1 g, 5 g, and 1 g of hmb + 5 g of cr, respectively. the hypotheses were tested by two-way repeated-measures analysis of variance (anova). results: there were no significant differences in cholesterol (chol.), triglyceride (tg), and low-density lipoprotein (ldl) levels after the post-test and 2 weeks of non-training. there were significant differences in high-density lipoprotein (hdl) in post-test between groups of weight training and hmb (p = 0.000), weight training and hmb + cr (p = 0.002), cr and hmb (p = 0.000), and cr and hmb + cr (p = 0.001). the weight training and hmb (p = 0.000), weight training and hmb + cr (p = 0.003), cr and hmb (p 0.000) =), and cr and hmb + cr groups (p = 0.001) were significantly different in 2 weeks of non-training. conclusion: six-week weight training with combined hmb and cr supplement and 2 weeks of non-training can significantly change the concentrations of some blood biochemical factors in male powerlifting athletes.