usage of phenytoin in treatment of severe headache in covid-19 patients

Covid-19 is a viral infection transmitted through the respiratory system, caused by coronavirus type 2 usually get excess to the body through flügge microdroplet of an infected person to a healthy one with air although direct contact and aerosol may be another route for transmission. this is a prospective study of 500 patients (63% women) conducted in a medical city in baghdad. in a study patients’ collection started in aug 2020 for six weeks. they followed for at least six months after they recovered from covid-19. among 500 patients included 53.4% were male (out of those 118 were complain of severe headaches 23.6%), while females comprise about 46.6% of total patients of that 13% had severe headaches. the highest age group with severe headaches was (60-65) years coming next (51-55) years. group a had a partial response to drugs used although more than 60% respond to a combination of ibuprofen and acetaminophen, while in group b good control of headache was achieved (80%) when adding phenytoin to treatment protocol during and after the acute stage of the disease. there is controversy about the treatment of headaches caused by covid-19 but for sure, acetomenaphin combined with nsadi drugs is the best and safe choice. in refractory cases, antiepileptic drugs like phenytoin are added to achieve freedom of pain and for a long-term period.