effect of pb-exposure on serum calcium and phosphorus components among pb-battery manufacturing workers

Most of the studies assessed the effect of pb-exposure on serum total calcium and phosphorus. this study assessed the effect of pb- exposure on serum total calcium (tca^2+) and phosphorus (p) components such as corrected calcium (cca^2+), ionized calcium (ica^2+), percentage of ica^2+from tca^2+, percentage of ica^2+from cca^2+, ratios of tca^2+: p, cca^2+: p, ica^2+: p and product of ca^2+ and p in workers of different category of pb-exposure. this study enrolled 176 male pb-exposed workers and categorized into two groups based on blood lead levels (blls) recommended by bei-acgih. the low pb-exposure group is 86 workers with their blls is ≤ 30 µg/dl and high pb- d exposure is 90 workers with their blls is > 30 µg/dl). 80 healthy workers with no occupational exposure to pb were included them as control for the comparison. the serum calcium, phosphorus and albumin concentrations were done by using diagnostic kit methods. blls were estimated by using the flame atomic absorption spectrometric method. the serum tca^2+, cca^2+ and ica^2+ were significantly decreased in low and high pb-exposure groups as compared to control. the ratios of tca2+: p, cca^2+: p, ica^2+: p was significantly decreased in the high pb-exposure as compared to low pb–exposure and controls. product of tca^2+x p was significantly increased in the high pb-exposure group as compared to low pb- exposure. a negative association was noted between blls and serum tca^2+, ica^2+and cca^2+ in a high pb- exposure group. the components of serum calcium and phosphorus were significantly altered in pb- exposed workers.