بررسی تاثیر بیهوشی با پروپوفول بر برخی فاکتورهای خونی ماهی کپورعلف خوار Ctenopharyngodon Iddella

Propofol as an anesthetic drug is well known in human and veterinary medicine that has specific anestheticeffects. but there is no report about the anesthesia in grass carp and its side effects on blood parameterof fish. for this purpose, 120 grass carp with average weight between 150-420 g were chosen. fisheswere divided randomly into 12 groups of 10 fish each. two groups were considered as control. the other10 groups were anesthetized with bath and i.v. injection methods by propofol in different concentrations(2, 4, 6, 8 and 10 mg/l) and doses (2, 4, 6, 8 and 10 mg/kg). at the time of anesthesia and 4 days afterrecovery blood parameters were measured for all groups. blood samples were taken from the caudalvein and total erythrocyte and leukocyte count, hemoglobin (hb.), hematocrit (pcv), mean corpuscularvolume (mcv), mean corpuscular hemoglobin (mch), mean corpuscular hemoglobin concentration(mchc) were measured for all groups. the data were analyzed by one way analysis of variance by spss11.5 software. according to result, at the time of anesthesia with propofol in bath method, the mean ofhematocrit and erythrocyte count were significantly higher than the control group. also in 4 days afteranesthesia, mean leukocyte count in 4, 6 and 8 mg/l was significantly higher than control group. in injectiongroup at the time of anesthesia with propofol, the mean of hematocrit and erythrocyte count weresignificantly higher than control group. at the time of anesthesia the mean of mchc was significantlylower than the control group, also in 4 days after anesthesia with propofol, the mean of hemoglobin andmchc were significantly lower than control group.keywords: anesthesia, hematology, grass carp, ctenopharyngodon iddella, propofol