Electrochemical oxidation and determination of methocarbamol at multi-walled carbon nanotubes-modified glassy carbon electrode

A simple and rapid voltammetric oxidation of methocarbamol was investigated. in ph 3.0 phosphate buffer,methocarbamol shows an irreversible oxidation peak at about 1.28 v at a multi-walled carbon nanotube (mwcnt)-modified glassy carbon electrode. the cyclic voltammetric results indicate that mwcnt-modified glassy carbon electrode showed that methocarbamol at 12 μl of mwcnt,the oxidation sites of glassy carbon was adsorbed by mwcnt which increased only the current sensitivity. under optimized conditions,the concentration range and detection limit are 6.0×10-6 to 1.0×10-4 m and 4.22×10-6 m,respectively for methocarbamol. the proposed method was successfully applied to methocarbamol determination in pharmaceutical samples. the analytical performance of this sensor has been evaluated for the detection of analyte in urine sample. © 2016 by cee.