Application of Cu(II) nanocomplex modified graphite screen printed electrode to improve the sensitivity and selectivity for epinephrine detection

A cu(ii) nanocomplex,[cucl2(salophen)].h2o [salophen=o-phenylenediaminebis(salicylidenaminato)],was synthesized. the electrochemical properties of the as-prepared cu(ii) nanocomplex modified graphite screen printed electrode (cu/spe) were investigated using cyclic voltammetry (cv) and differential pulse voltammetry (dpv). moreover,as a nanosensor for the determination of epinephrine the cu/spe exhibited excellent electrocatalytic activity for the oxidation of epinephrine with a faster electron-transfer rate. the dpv technique was used for the trace determination of epinephrine. the dependence of current vs. concentration was linear from 10.0 to 600.0 µm with a regression coefficient of 0.9975,and the detection limit of epinephrine was 2.5±0.05 µm. finally,the method was applied to the selective and precise analysis of epinephrine in epinephrine injection. © 2017 by cee (center of excellence in electrochemistry).