Utilization of acetaminophen as a homogeneous electrocatalyst for n-acetyl-l-cysteine oxidation at the surface of carbon paste electrode

The utilization of acetaminophen (ac) as a homogeneous electrocatalyst in the presence of n-acetyl-l-cysteine (nac) at the surface of carbon paste electrode (cpe) modified with multi-walled carbon nanotubes (mwcnt) has been surveyed in aqueous medium using double step potential chronoamperometry (cha),cyclic voltammetry (cv) and differential pulse voltammetry (dpv) methods. though,nac itself shows a very negligible electrochemical response at bare cpe,the response could be greatly increased in the presence of acetaminophen at mwcnt paste electrode (mwcnt-cpe) which enables a sensitive electrochemical determination of the nac. the kinetic parameters such as transfer coefficient (α),the apparent diffusion coefficient (dapp) and the chemical reaction rate constant (kh) were calculated 0.33,5.56×10-6 cm2 s-1 and 1.35×102 cm3 mol-1 s-1,respectively. a linear calibration range of 1.0×10-6 m-3.0×10-5 m and detection limit of 3.9×10-7 m were obtained for determination of nac at mwcnt-cpe using dpv. the offered method is useful for the routine analysis of nac in real sample. © 2015 by cee (center of excellence in electrochemistry).