Rapid Differential Pulse Voltammetric Determination of Galantamine on the Simple Glassy Carbon Electrode; Alternative for the Standard Methods

The electrochemical behavior of galantamine (gal) in aqueous media has beenexamined by cyclic and differential pulse voltammetry. the voltammograms wererecorded with ?a utolab fra2 potentiostat-galvanostat. a three-electrode system wasused with a glassy carbon as working electrode, a platinum rod as the counter electrodeand an ag/agcl as the reference electrode. all tests were carried out under roomtemperature and n2 atmosphere. the ph strongly affects the peak potential of gal. thebest analytical response was obtained at ph 2.0. the cathodic peak currents wereproportional to gal concentrations in the range of 0.1–10 mm under the optimizedexperimental conditions. the detection limit was 0.02 mm. the effect of potential scanrate on the peak potential and peak current of gal was investigated. the correlation of thepeak currents against v1/2 (v is the scan rate) is linear, which is very similar to a diffusioncontrolledprocess. proposed method applied to analysis of commercial tablets,successfully.